Karen was most recently seen in global smash hit AVENGERS: INFINITY WAR, and in box office sensation JUMANJI as the only female lead opposite Kevin Hart, Dwayne Johnson, and Jack Black for Columbia Pictures and director Jake Kasdan. She can also be seen in the worldwide hit GUARDIANS OF THE GALAXY 2, in which she reprised her role as Nebula opposite Chris Pratt, Zoe Saldana, and Kurt Russell, and, again directed by James Gunn. Other film credits include, James Ponsoldt’s THE CIRCLE with Tom Hanks and Emma Watson, Adam McKay’s Best Picture nominated THE BIG SHORT and Blumhouse horror OCULUS. Karen will also be seen starring opposite Harrison Ford and Dan Stevens in THE CALL OF THE WILD which is due to be released December 2019. Karen's television credits include ABC comedy series SELFIE, BBC drama WE'LL TAKE MANHATTE, and BBC’s critically-acclaimed series DOCTOR WHO.
Karen’s directorial debut THE PARTY’S JUST BEGINNING, a project which she also wrote, produced, and starred in, had its US premiere at the Tribeca Film Festival 2018.